USMLE GUIDE TO HIGH SCORE MORE THAN 250

USMLE  GUIDE TO HIGH SCORE MORE THAN 250 by Mirzadani

WEEKS PRENATAL DIAGNOSTIC TESTING

Prenatal Diagnostic Testing Schedule

WEEKS  PRENATAL  DIAGNOSTIC TESTING

Prenatal visits  

• Weeks 0-28: Every 4 weeks. 
• Weeks 29-35: Every 2 weeks. 
• Weeks 36-birth: Every week. 

Initial visit :

Heme:  CBC, Rh factor ,  type  and  screen.

Infectious disease:

UA and culture,  rubella  antibody titer , HBsAg,
RPR/VDRL, cervical gonorrhea and chlamydia, PPD, HIV,  Pap
smear (to check for dysplasia). Consider HCV and varicella based
on history.

If indicated: HbA, sickle cell screening.
Discuss genetic screening:  Tay-Sachs disease, cystic fibrosis.

9- 14  weeks :

Offer PAPP-A +  nuchal transparency + free  B-hCG +/- chorionic
villus sampling  (CVS)

15-22 weeks :

Offer maternal  serum a-fetoprotein  (MSAFP)  or quad screen  (AFP,
estriol,  P-hCG, and inhibin A)  +/- amniocentesis.

18-20 weeks :

Ultrasound for full  anatomic screen.

24-28 weeks : 

One-hour glucose  challenge test for gestational diabetes screen.

28-30 weeks :

RhoGAM for  Rh-8 women (after antibody screen).

35-40 weeks :

Group  B  strep  culture  (GBS);  repeat CBC.

34-40 weeks :

Cervical chlamydia  and  gonorrhea cultu res,  HIV,  RPR  in high-risk patients.

Dix Hallpike maneuver for BPPV

Spinal Cord Lesions - USMLE high yield concepts

Common Antibodies and Their Disease Associations

Common Antibodies and Their Disease Associations

ANTIBODY  DISEASE ASSOCIATION

1. ANA  SLE 
2. Anti-CCP  RA 
3. Anti  centromere  CREST  syndrome 
4. Anti-dsDNA  SLE 
5. Anti  histone  Drug-induced  SLE 
6. Anti-Jo- 1  Polymyositis/dermatomyositis 
7. Anti  mitochondrial  Primary biliary cirrhosis 
8. Antinuclear  Scleroderma 
9. Anti-Scl-70  Scleroderma 
10. Anti-Sm  SLE 
11. Anti-smooth muscle  Autoimmune hepatitis 
12. Antitopoisomerase I  Scleroderma 
13. Anti-TSHR  Graves'  disease 
14. c-ANCA  Vasculitis, especially Wegener's 
15. p-ANCA  Vasculitis,  microscopic polyangiitis 
16. Rheumatoid factor  RA 
17. Ul  RNP antibody  Mixed connective tissue disease

Common AIDS-defining illnesses and Opportunistic infections

Common AIDS-defining illnesses:

• Esophageal candidiasis 
• CMV retinitis 
• Kaposi's sarcoma 
• CNS  lymphoma, toxoplasmosis, PML 
• P jiroveci pneumonia  or  recurrent bacterial  pneumonia 
• HIV encephalopathy 
• Disseminated  mycobacterial or fungal infection 
• Invasive cervical cancer

Thrombogenesis and its deficiencies