Vascular and immunologic manifestations of infective endocarditis

Vascular & immunologic manifestations of infective endocarditis:

Duke Criteria

Vascular phenomena:

• Systemic arterial emboli (focal neurologic deficits, renal or splenic infarcts)
• Septic pulmonary infarcts
• Mycotic aneurysm
• Conjunctival hemorrhages
• Janeway lesions- Macular, erythematous, non-tender lesions on the palms and soles.

Immunologic phenomena:

• Osler's nodes- Painful, violaceous nodules seen on the fingertips & toes.
• Roth spots- Edematous and hemorrhagic lesions of the retina.
• Glomerulonephritis
• Arthritis or positive rheumatoid factor.